Juventix Blogs

Women’s Sexual Health

By April 7, 2023April 16th, 2024No Comments

Women’s sexual health is important to emotional and physical well-being. However, for many women who are older than 40 and who have gone through menopause, physical desire is not the primary motivation for sex as it was in their younger years.

A women might be motivated to have sex to feel closer to her partner or to demonstrate her feelings. However, sexual satisfaction differs for everyone with many factors influencing sexual response. Some of these factors are time, the overall relationship, romance, routine and pleasure.

Timing, relationship matters, romance and routine can be easily addressed and there are specific answers that can be agreed upon between partners. However, physical issues can be problematic, and the answers may not be so readily available.

Society has addressed the male problem of erectile dysfunction with various treatments and medications even surgery. Little, if anything, has been done for women especially on the topic of anorgasmia.

Anorgasmia is delayed, infrequent or absent orgasms or less intense orgasms after sexual arousal and adequate sexual stimulation.

An orgasm is a peak feeling of intense pleasure in response to stimulating sexual activity.

Female orgasmic disorder is another term for the spectrum of problems with orgasms. The word “anorgasmia” specifically refers to not being able to have an orgasm, but the term is collectively used as shorthand for all female orgasmic disorders.

Anorgasmia, or female orgasmic disorder, is defined as experiencing any of these symptoms.

  • Delayed orgasm
  • Total absence of orgasm
  • Fewer orgasms
  • Less intense orgasms


Sexual arousal and orgasms are complex reactions to various physical, emotional and psychological factors. Difficulties with one or more of these factors usually leads to this problem.

Personal and Psychological Factors

Behaviors, background or mental well-being may contribute

  • Past sexual or emotional abuse
  • Poor body image
  • Cultural or religious background
  • Guilt or embarrassment
  • Stressors
  • Mental health issues
  • Lack of knowledge about sexual stimulation

Relationship Factors

Problems with your partner may contribute to lack of orgasms

  • No emotional intimacy
  • Conflicts
  • Poor communication
  • Lack of trust
  • Partners sexual dysfunction such as erectile dysfunction

Physical Etiology

A wide range of illnesses, physical problems and medications such as ,

  • Health issues- conditions such as diabetes, overactive bladder or multiple sclerosis
  • Gynecological issues- prior tissue damage from gynecologic surgery such as hysterectomy or cancer
  • Medications- a wide spectrum of medications can inhibit orgasms especially blood pressure medications, antipsychotic drugs, antihistamines and antidepressants especially selective serotonin reuptake inhibitors
  • Excessive alcohol which suppresses the nervous system
  • Smoking which limits overall blood supply to an area
  • Menopause which can change the tissue environment and contribute to overall sexual dysfunction

Related Sexual Disorders/Other Physiologic Issues

  • Problems with sexual arousal
  • Little to no desire
  • Involuntary tightening of the vagina called vaginismus
  • Dryness
  • Painful intercourse


Possible treatments include lifestyle modification, therapy and medications

  • Education
  • Counseling/therapy
  • Home exercising
  • Sexual enhancement devices- stimulate and increase blood flow


Estrogen therapy which can improve blood flow to the vaginal tissues and improve lubrication.

Long term use associated with a risk of breast cancer and cardiovascular disease.

Testosterone therapy for those who have extremely low testosterone levels.

Side effects may include acne, increase body hair, decline in HDL cholesterol and other risks similar to estrogen.

ADDYI (flibanserin) originally developed as an anti-depressant is a FDA approved daily pill used as a treatment for low sexual desire in premenopausal women. Potentially serious side effects are low blood pressure, dizziness and fainting.

This drug should not be used to treat low sexual desire caused by a medical or mental disorder.

This drug was rejected twice in 2010 and again in 2013. In 2015, it was approved and deemed effective in 10% of women.

Women who have taken this drug with alcohol had twice as many serious accidents especially car accidents then the control group.

ADDYI is in the class of drugs called SSRI. It has been proven that this class of drugs causes orgasmic dysfunction.

VYLEESI (bremelanotide) is an injectable medication, FDA approved for the treatment of low sexual desire in premenopausal women.

VYLEESI activates the melanocortin receptors but the mechanism by which it improves sexual desire is unknown.

Studies showed 25% of patients treated had a slight increase in their sexual desire scores while 17% of the placebo group had the same. Additionally, 35% of patients treated with VYLEESI had a decrease in the same scores while 31% who took placebo had the same decrease.

VYLEESI has a common side effect of nausea and vomiting, flushing, injection site reactions and headache. 40% of patients experienced nausea. 1% had darkening of the skin which did not go away in half of this group after stopping the medication.


The O-Shot was invented by Dr. Charles Runels of Fairhope, Alabama in 2011. He and his girlfriend got the idea whether the same procedure done to tighten the skin and rejuvenate the face could be used “down there”. The rest is history, and the O-Shot is being used worldwide.

Platelet Rich Plasma is an autologous blood concentrate, rich in growth factors, cytokines and bioactive proteins, used in all fields of medicine where tissues need to be regenerated or repaired. As an autologous concentrate, there are no side effects and can be used in all age groups.

The O-Shot is Platelet Rich Plasma injected into the vagina at the G-spot and the clitoris. The platelets contain growth factors that stimulate the growth of new cells in the injected area which improves nerve function and stimulates blood supply to the area.

Overall, the O-Shot improves stimulation, sensitivity, arousal, lubrication and orgasms. In addition to the improvement gained in sexual pleasure, sensitivity and better lubrication, the O-Shot aids in stress urinary incontinence. Stress incontinence can be the result of 25% of vaginal deliveries and it causes leakage of urine upon sneezing, jumping or coughing.

Those who receive the O-Shot have reported;

  • Younger smoother labial skin
  • Greater arousal from stimulation
  • Increased sexual desire
  • Increased lubrication
  • Decreased urinary incontinence
  • Less painful sexual intercourse

It is reported that 50 million females in the US alone suffer from sexual problems that have basically been ignored by the big pharma companies.

Juventix Regenerative Medical is an industry leader in the regenerative medical field. Our Platelet Rich Plasma Kits, used for the O-Shot procedure, are FDA approved. The O-Shot procedure takes about 30 minutes in the office. Once your blood is taken, it is centrifuged and activated by our LED Activator. This releases the highest amount of cytokines and growth factors from the PRP. Using a very small needle, the PRP is injected into the anterior vaginal area and into the clitoris. Discomfort is minimal or none at all, due to the prior application of a numbing cream and some applied ice. Most women report and slight pinch during the procedure.

After the procedure, one can return to normal activity. Over the next few days to weeks, increased arousal, lubrication, less urinary incontinence and ability to reach orgasm is typically reported.

As with any procedure, the pro’s and con’s should be addressed with a professional healthcare provider.


Turk J Obstet Gynecol 2019 Dec;16(4):228-234  PMID 32231853

Objective: To investigate the effect of platelet Rich Plasma (PRP) injection to the lower one third of the anterior vaginal wall on sexual dysfunction, orgasm, and genital perception in women with sexual dysfunction.

Conclusion: As a minimally invasive method, PRP administration to the distal anterior vaginal wall may improve female sexuality with high satisfaction

Int J Res Public Health 2022 Apr 26;19(9):5284. PMID 35564681

Conclusion: The administration of PRP in genital rejuvenation to improve the quality of sexual life was investigated. The effect of PRP injection to the lower one third of the anterior vaginal wall on sexual function, orgasm and genital perception in women with sexual dysfunction was studied. This study revealed that a minimally invasive method, PRP administration may improve female sexuality along with higher satisfaction. Another study conducted on 68 women aged 32 to 97 indicated that the O-Shot is a satisfactory solution for women having stress incontinence, overactive bladder, lack of lubrication and sexual dysfunction such as lack of libido, arousal and dyspareunia. The results show that 94% of these patients were satisfied, however 6% of patients with overactive bladder did not indicate improvement.

Clin Dermatol 2022 May-June;40(3):259-264 PMID 34838658

Objective: Female genitourinary treatments in aesthetics utilize energy-based treatments and other noninvasive modalities. These include platelet rich plasma and others with an objective to treat sexual dysfunction and symptoms of genitourinary syndrome.

Conclusion: this abstract concluded, “the body of evidence is growing for the use of these modalities to improve signs and symptoms of genitourinary syndrome and sexual function associated with menopause as well as rejuvenating the appearance of the external female genitalia”.


Regenerative Regards,


Dr. Robert McGrath




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